Indications

Cardiovascular
• Hypertension
• Hypercholesterolemia
• Atherosclerosis

Endocrine
• Diabetes
• Obesity

Urinary
• Diabetic Nephropathy
• Nephrotoxicity Due To Chemotherapy (Cisplatin)
• Kidney Stones

Musculoskeletal
• Gout

Other
• Wound Healing (Topically)
• Cancer

Actions

• Antihypertensive
• Antihyperlipidemic
• Antidiabetic
• Antigout
• Antioxidant
• Antilithic
• Nephroprotective
• Hepatoprotective
• Antiinflammatory
• Diuretic
• Anxiolytic (Mild)
• Sedative (Mild )

Constituents

• Organic Acids (Citric Acid, Malic Acid, And Tartaric Acid)
• Mucilage
• Polyphenols
• Anthocyanidin (Cyanidin And Delphinidin)
• Tannins

Pharmacology

- ACE inhibitor
• Inhibits α -amylase and α -glucosidase
• potassium sparing diuretic

Safety

• generally considered safe to consume long-term
• LD50 > 5000 mg/kg (i.e. very safe )

Interactions

• cisplatin • hibiscus may reduce nephrotoxicity
• hydrochlorothiazide • may potentiate diuretic effects

References

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